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Commitment toward the natural T (iNKT) cell lineage occurs at the CD4(+)8(+) stage of thymic ontogeny
T lineage commitment occurs in a discrete, stage-specific manner during thymic ontogeny. Intrathymic precursor transfer experiments and the identification of CD4(+)8(+) double-positive (DP), Vα14Jα18 natural T (iNKT) cells suggest that commitment to this lineage might occur at the DP stage. Neverthe...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC555981/ https://ncbi.nlm.nih.gov/pubmed/15792999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408449102 |
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