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Commitment toward the natural T (iNKT) cell lineage occurs at the CD4(+)8(+) stage of thymic ontogeny

T lineage commitment occurs in a discrete, stage-specific manner during thymic ontogeny. Intrathymic precursor transfer experiments and the identification of CD4(+)8(+) double-positive (DP), Vα14Jα18 natural T (iNKT) cells suggest that commitment to this lineage might occur at the DP stage. Neverthe...

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Bibliografiske detaljer
Main Authors: Bezbradica, Jelena S., Hill, Timothy, Stanic, Aleksandar K., Van Kaer, Luc, Joyce, Sebastian
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC555981/
https://ncbi.nlm.nih.gov/pubmed/15792999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408449102
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