Chemokine CCL2–CCR2 Signaling Induces Neuronal Cell Death via STAT3 Activation and IL-1β Production after Status Epilepticus

Elevated levels of chemokine C-C motif ligand 2 (CCL2) and its receptor CCR2 have been reported in patients with temporal lobe epilepsy and in experimental seizures. However, the functional significance and molecular mechanism underlying CCL2–CCR2 signaling in epileptic brain remains largely unknown...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Neurosci
Hlavní autoři: Tian, Dai-Shi, Peng, Jiyun, Murugan, Madhuvika, Feng, Li-Jie, Liu, Jun-Li, Eyo, Ukpong B., Zhou, Li-Jun, Mogilevsky, Rochelle, Wang, Wei, Wu, Long-Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2017
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559763/
https://ncbi.nlm.nih.gov/pubmed/28716963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0315-17.2017
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky