Chemokine CCL2–CCR2 Signaling Induces Neuronal Cell Death via STAT3 Activation and IL-1β Production after Status Epilepticus

Elevated levels of chemokine C-C motif ligand 2 (CCL2) and its receptor CCR2 have been reported in patients with temporal lobe epilepsy and in experimental seizures. However, the functional significance and molecular mechanism underlying CCL2–CCR2 signaling in epileptic brain remains largely unknown...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Tian, Dai-Shi, Peng, Jiyun, Murugan, Madhuvika, Feng, Li-Jie, Liu, Jun-Li, Eyo, Ukpong B., Zhou, Li-Jun, Mogilevsky, Rochelle, Wang, Wei, Wu, Long-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559763/
https://ncbi.nlm.nih.gov/pubmed/28716963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0315-17.2017
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