A GluN2B-Selective NMDAR Antagonist Reverses Synapse Loss and Cognitive Impairment Produced by the HIV-1 Protein Tat

HIV-associated neurocognitive disorder (HAND) affects approximately half of HIV-infected patients. Loss of synaptic connections is a hallmark of many neurocognitive disorders, including HAND. The HIV-1 protein transactivator of transcription (Tat) disrupts synaptic connections both in vitro and in v...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Neurosci
Egile Nagusiak: Raybuck, Jonathan D., Hargus, Nicholas J., Thayer, Stanley A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2017
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559761/
https://ncbi.nlm.nih.gov/pubmed/28716964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0226-17.2017
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