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A GluN2B-Selective NMDAR Antagonist Reverses Synapse Loss and Cognitive Impairment Produced by the HIV-1 Protein Tat
HIV-associated neurocognitive disorder (HAND) affects approximately half of HIV-infected patients. Loss of synaptic connections is a hallmark of many neurocognitive disorders, including HAND. The HIV-1 protein transactivator of transcription (Tat) disrupts synaptic connections both in vitro and in v...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | J Neurosci |
|---|---|
| Prif Awduron: | , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Society for Neuroscience
2017
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5559761/ https://ncbi.nlm.nih.gov/pubmed/28716964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0226-17.2017 |
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