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Ca(2+)-regulated structural changes in troponin

Troponin senses Ca(2+) to regulate contraction in striated muscle. Structures of skeletal muscle troponin composed of TnC (the sensor), TnI (the regulator), and TnT (the link to the muscle thin filament) have been determined. The structure of troponin in the Ca(2+)-activated state features a nearly...

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Detalles Bibliográficos
Main Authors: Vinogradova, Maia V., Stone, Deborah B., Malanina, Galina G., Karatzaferi, Christina, Cooke, Roger, Mendelson, Robert A., Fletterick, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC555973/
https://ncbi.nlm.nih.gov/pubmed/15784741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408882102
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