Temperature-sensitive protein–DNA dimerizers

Programmable DNA-binding polyamides coupled to short peptides have led to the creation of synthetic artificial transcription factors. A hairpin polyamide–YPWM tetrapeptide conjugate facilitates the binding of a natural transcription factor Exd to an adjacent DNA site. Such small molecules function a...

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Detalhes bibliográficos
Main Authors: Hauschild, Karl E., Metzler, Renee E., Arndt, Hans-Dieter, Moretti, Rocco, Raffaelle, Marni, Dervan, Peter B., Ansari, Aseem Z.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC555971/
https://ncbi.nlm.nih.gov/pubmed/15781856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501289102
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