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Enhanced Nutrient Transport Improves the Depth-Dependent Properties of Tri-Layered Engineered Cartilage Constructs with Zonal Co-Culture of Chondrocytes and MSCs

Biomimetic design in cartilage tissue engineering is a challenge given the complexity of the native tissue. While numerous studies have generated constructs with near-native bulk properties, recapitulating the depth-dependent features of native tissue remains a challenge. Furthermore, limitations in...

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Detalhes bibliográficos
Publicado no:Acta Biomater
Main Authors: Kim, Minwook, Farrell, Megan J., Steinberg, David R., Burdick, Jason A., Mauck, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559709/
https://ncbi.nlm.nih.gov/pubmed/28629894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2017.06.025
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