High Mesenchymal Stem Cell Seeding Densities in Hyaluronic Acid Hydrogels Produce Engineered Cartilage with Native Tissue Properties

Engineered cartilage based on adult mesenchymal stem cells (MSCs) is an alluring goal for the repair of articular defects. However, efforts to date have failed to generate constructs with sufficient mechanical properties to function in the demanding environment of the joint. Our findings with a nove...

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Библиографические подробности
Главные авторы: Erickson, Isaac E., Kestle, Sydney R., Zellars, Kilief H., Farrell, Megan J., Kim, Minwook, Burdick, Jason A., Mauck, Robert L.
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389207/
https://ncbi.nlm.nih.gov/pubmed/22546516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2012.04.033
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