Social isolation suppresses actin dynamics and synaptic plasticity through ADF/cofilin inactivation in the developing rat barrel cortex

Exposure to a stressful environment early in life can cause psychiatric disorders by disrupting circuit formation. Actin plays central roles in regulating neuronal structure and protein trafficking. We have recently reported that neonatal isolation inactivated ADF/cofilin, the actin depolymerizing f...

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Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Tada, Hirobumi, Miyazaki, Tomoyuki, Takemoto, Kiwamu, Jitsuki, Susumu, Nakajima, Waki, Koide, Mayu, Yamamoto, Naoko, Taguchi, Akiko, Kawai, Honami, Komiya, Kasane, Suyama, Kumiko, Abe, Hiroki, Sano, Akane, Takahashi, Takuya
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559554/
https://ncbi.nlm.nih.gov/pubmed/28814784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08849-3
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