Gpr124 is essential for blood–brain barrier integrity in central nervous system disease

Although blood–brain barrier (BBB) compromise is central to the etiology of diverse central nervous system (CNS) disorders, endothelial receptor proteins that control BBB function are poorly defined. The endothelial G-protein-coupled receptor (GPCR) Gpr124 has been reported to be required for normal...

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Publicado no:Nat Med
Main Authors: Chang, Junlei, Mancuso, Michael R, Maier, Carolina, Liang, Xibin, Yuki, Kanako, Yang, Lu, Kwong, Jeffrey W, Wang, Jing, Rao, Varsha, Vallon, Mario, Kosinski, Cynthia, Zhang, J J Hailing, Mah, Amanda T, Xu, Lijun, Li, Le, Gholamin, Sharareh, Reyes, Teresa F, Li, Rui, Kuhnert, Frank, Han, Xiaoyuan, Yuan, Jenny, Chiou, Shin-Heng, Brettman, Ari D, Daly, Lauren, Corney, David C, Cheshier, Samuel H, Shortliffe, Linda D, Wu, Xiwei, Snyder, Michael, Chan, Pak, Giffard, Rona G, Chang, Howard Y, Andreasson, Katrin, Kuo, Calvin J
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559385/
https://ncbi.nlm.nih.gov/pubmed/28288111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4309
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