Suppression of lymphocyte functions by plasma exosomes correlates with disease activity in patients with head and neck cancer

PURPOSE: Head and neck cancers (HNC) often induce profound immunosuppression which contributes to disease progression and interferes with immune-based therapies. Body fluids of HNC patients are enriched in exosomes potentially engaged in negative regulation of anti-tumor immune responses. The presen...

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Bibliographic Details
Published in:Clin Cancer Res
Main Authors: Ludwig, Sonja, Floros, Theofanis, Theodoraki, Marie-Nicole, Hong, Chang-Sook, Jackson, Edwin K., Lang, Stephan, Whiteside, Theresa L.
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559308/
https://ncbi.nlm.nih.gov/pubmed/28400428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-2819
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