Plasma metabolomics reveals membrane lipids, aspartate/asparagine and nucleotide metabolism pathway differences associated with chloroquine resistance in Plasmodium vivax malaria

BACKGROUND: Chloroquine (CQ) is the main anti-schizontocidal drug used in the treatment of uncomplicated malaria caused by Plasmodium vivax. Chloroquine resistant P. vivax (PvCR) malaria in the Western Pacific region, Asia and in the Americas indicates a need for biomarkers of resistance to improve...

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Foilsithe in:PLoS One
Main Authors: Uppal, Karan, Salinas, Jorge L., Monteiro, Wuelton M., Val, Fernando, Cordy, Regina J., Liu, Ken, Melo, Gisely C., Siqueira, Andre M., Magalhaes, Belisa, Galinski, Mary R., Lacerda, Marcus V. G., Jones, Dean P.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2017
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559093/
https://ncbi.nlm.nih.gov/pubmed/28813452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182819
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