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Telomere biology and telomerase mutations in cirrhotic patients with hepatocellular carcinoma
Telomeres are repetitive DNA sequences at linear chromosome termini, protecting chromosomes against end-to-end fusion and damage, providing chromosomal stability. Telomeres shorten with mitotic cellular division, but are maintained in cells with high proliferative capacity by telomerase. Loss-of-fun...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5558955/ https://ncbi.nlm.nih.gov/pubmed/28813500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183287 |
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