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Exploiting the Ref-1-APE1 node in cancer signaling and other diseases: from bench to clinic
Reduction-oxidation factor 1-apurinic/apyrimidinic endonuclease (Ref-1/APE1) is a critical node in tumor cells, both as a redox regulator of transcription factor activation and as part of the DNA damage response. As a redox signaling protein, Ref-1/APE1 enhances the transcriptional activity of STAT3...
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Publicado no: | NPJ Precis Oncol |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group UK
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5558897/ https://ncbi.nlm.nih.gov/pubmed/28825044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-017-0023-0 |
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