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Identification of a role for TRIM29 in the control of innate immunity in the respiratory tract

The respiratory tract is heavily populated with innate immune cells, but the mechanisms that control such cells are poorly defined. Here we found that the E3 ubiquitin ligase TRIM29 was a selective regulator of the activation of alveolar macrophages, the expression of type I interferons and the prod...

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Bibliografske podrobnosti
izdano v:Nat Immunol
Main Authors: Xing, Junji, Weng, Leiyun, Yuan, Bin, Wang, Zhuo, Jia, Li, Jin, Rui, Lu, Hongbo, Li, Xian Chang, Liu, Yong-Jun, Zhang, Zhiqiang
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558830/
https://ncbi.nlm.nih.gov/pubmed/27695001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3580
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