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Identification of a role for TRIM29 in the control of innate immunity in the respiratory tract

The respiratory tract is heavily populated with innate immune cells, but the mechanisms that control such cells are poorly defined. Here we found that the E3 ubiquitin ligase TRIM29 was a selective regulator of the activation of alveolar macrophages, the expression of type I interferons and the prod...

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Detalhes bibliográficos
Publicado no:Nat Immunol
Main Authors: Xing, Junji, Weng, Leiyun, Yuan, Bin, Wang, Zhuo, Jia, Li, Jin, Rui, Lu, Hongbo, Li, Xian Chang, Liu, Yong-Jun, Zhang, Zhiqiang
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558830/
https://ncbi.nlm.nih.gov/pubmed/27695001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3580
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