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GPER Mediates Functional Endothelial Aging in Renal Arteries

Aging is associated with impaired renal artery function, which is partly characterized by arterial stiffening and a reduced vasodilatory capacity due to excessive generation of reactive oxygen species by NADPH oxidases (Nox). The abundance and activity of Nox depends on constitutive activity of the...

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Bibliographische Detailangaben
Veröffentlicht in:Pharmacology
Hauptverfasser: Meyer, Matthias R., Rosemann, Thomas, Barton, Matthias, Prossnitz, Eric R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558788/
https://ncbi.nlm.nih.gov/pubmed/28704834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000478732
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