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Contractile force generation by 3D hiPSC-derived cardiac tissues is enhanced by rapid establishment of cellular interconnection in matrix with muscle-mimicking stiffness

Engineering 3D human cardiac tissues is of great importance for therapeutic and pharmaceutical applications. As cardiac tissue substitutes, extracellular matrix-derived hydrogels have been widely explored. However, they exhibit premature degradation and their stiffness is often orders of magnitude l...

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Publicat a:Biomaterials
Autors principals: Lee, Soah, Serpooshan, Vahid, Tong, Xinming, Venkatraman, Sneha, Lee, Meelim, Lee, Jaecheol, Chirikian, Orlando, Wu, Joseph C., Wu, Sean M., Yang, Fan
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558787/
https://ncbi.nlm.nih.gov/pubmed/28384492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2017.03.039
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