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Sex differences in microRNA-mRNA networks: examination of novel epigenetic programming mechanisms in the sexually dimorphic neonatal hypothalamus

BACKGROUND: Sexual differentiation of the male brain, and specifically the stress circuitry in the hypothalamus, is primarily driven by estrogen exposure during the perinatal period. Surprisingly, this single hormone promotes diverse programs of sex-specific development that vary widely between diff...

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Bibliographic Details
Published in:Biol Sex Differ
Main Authors: Morgan, Christopher P., Bale, Tracy L.
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558756/
https://ncbi.nlm.nih.gov/pubmed/28810930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13293-017-0149-3
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