Transgenerational epigenetic programming via sperm microRNA recapitulates effects of paternal stress

Epigenetic signatures in germ cells, capable of both responding to the parental environment and shaping offspring neurodevelopment, are uniquely positioned to mediate transgenerational outcomes. However, molecular mechanisms by which these marks may communicate experience-dependent information acros...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Rodgers, Ali B., Morgan, Christopher P., Leu, N. Adrian, Bale, Tracy L.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2015
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640733/
https://ncbi.nlm.nih.gov/pubmed/26483456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1508347112
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