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Transgenerational epigenetic programming via sperm microRNA recapitulates effects of paternal stress

Epigenetic signatures in germ cells, capable of both responding to the parental environment and shaping offspring neurodevelopment, are uniquely positioned to mediate transgenerational outcomes. However, molecular mechanisms by which these marks may communicate experience-dependent information acros...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Rodgers, Ali B., Morgan, Christopher P., Leu, N. Adrian, Bale, Tracy L.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640733/
https://ncbi.nlm.nih.gov/pubmed/26483456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1508347112
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