Role of engineered metal oxide nanoparticle agglomeration in reactive oxygen species generation and cathespin B release in NLRP3 inflammasome activation and pulmonary toxicity

Incomplete understanding of the contributions of dispersants and engineered nanomaterial (ENM) agglomeration state to biological outcomes presents an obstacle for toxicological studies. Although reactive oxygen species (ROS) production is often regarded as the primary indicator of ENM bioactivity an...

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Detalhes bibliográficos
Publicado no:Inhal Toxicol
Main Authors: Sager, Tina M., Wolfarth, Michael, Leonard, Stephen S., Morris, Anna M., Porter, Dale W., Castranova, Vincent, Holian, Andrij
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558090/
https://ncbi.nlm.nih.gov/pubmed/27919184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/08958378.2016.1257664
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