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An Evaluation of the in vivo Safety of Nonporous Silica Nanoparticles: Ocular Topical Administration versus Oral Administration

Nonporous silica nanoparticles (SiNPs) have potential as promising carriers for ophthalmic drugs. However, the in vivo safety of ocular topical SiNPs remains unclear. This study investigated the in vivo safety of oral and ocular topical applications of 100 nm-sized SiNPs in Sprague-Dawley rats. The...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Kim, Martha, Park, Joo-Hee, Jeong, Hyejoong, Hong, Jinkee, Choi, Woo Sung, Lee, Byung-Han, Park, Choul Yong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557988/
https://ncbi.nlm.nih.gov/pubmed/28811672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08843-9
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