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An Evaluation of the in vivo Safety of Nonporous Silica Nanoparticles: Ocular Topical Administration versus Oral Administration

Nonporous silica nanoparticles (SiNPs) have potential as promising carriers for ophthalmic drugs. However, the in vivo safety of ocular topical SiNPs remains unclear. This study investigated the in vivo safety of oral and ocular topical applications of 100 nm-sized SiNPs in Sprague-Dawley rats. The...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Kim, Martha, Park, Joo-Hee, Jeong, Hyejoong, Hong, Jinkee, Choi, Woo Sung, Lee, Byung-Han, Park, Choul Yong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557988/
https://ncbi.nlm.nih.gov/pubmed/28811672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08843-9
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