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An Evaluation of the in vivo Safety of Nonporous Silica Nanoparticles: Ocular Topical Administration versus Oral Administration

Nonporous silica nanoparticles (SiNPs) have potential as promising carriers for ophthalmic drugs. However, the in vivo safety of ocular topical SiNPs remains unclear. This study investigated the in vivo safety of oral and ocular topical applications of 100 nm-sized SiNPs in Sprague-Dawley rats. The...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Kim, Martha, Park, Joo-Hee, Jeong, Hyejoong, Hong, Jinkee, Choi, Woo Sung, Lee, Byung-Han, Park, Choul Yong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557988/
https://ncbi.nlm.nih.gov/pubmed/28811672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08843-9
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