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Identification, replication and characterization of epigenetic remodelling in the aging genome: a cross population analysis

Aging is a complex biological process regulated by multiple cellular pathways and molecular mechanisms including epigenetics. Using genome-wide DNA methylation data measured in a large collection of Scottish old individuals, we performed discovery association analysis to identify age-methylated CpGs...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Li, Shuxia, Christiansen, Lene, Christensen, Kaare, Kruse, Torben A., Redmond, Paul, Marioni, Riccardo E., Deary, Ian J., Tan, Qihua
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557932/
https://ncbi.nlm.nih.gov/pubmed/28811542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08346-7
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