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A novel permutation test for case-only analysis identifies epistatic effects on human longevity in the FOXO gene family
Genetic interactions or epistasis could make a substantial contribution to variation in human complex traits including longevity. However, detecting epistatic interactions in high dimensional datasets is difficult due to various reasons including multiple testing of correlated tests. We introduce a...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3714332/ https://ncbi.nlm.nih.gov/pubmed/23607278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12092 |
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