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Histone deacetylase 6 (HDAC6) is an essential factor for oocyte maturation and asymmetric division in mice

Tubastatin A (Tub-A), a highly selective histone deacetylase 6 (HDAC6) inhibitor, has been widely used as a cytotoxic anticancer agent, or for the treatment of patients with asthma. However, the potential toxicity of Tub-A on oocyte maturation and asymmetric division is still unclear. Therefore, the...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Zhou, Dongjie, Choi, Yun-Jung, Kim, Jin-Hoi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557833/
https://ncbi.nlm.nih.gov/pubmed/28811599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08650-2
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