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Ligand binding modes from low resolution GPCR models and mutagenesis: chicken bitter taste receptor as a test-case
Bitter taste is one of the basic taste modalities, warning against consuming potential poisons. Bitter compounds activate members of the bitter taste receptor (Tas2r) subfamily of G protein-coupled receptors (GPCRs). The number of functional Tas2rs is species-dependent. Chickens represent an intrigu...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5557796/ https://ncbi.nlm.nih.gov/pubmed/28811548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08344-9 |
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