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Retrotransposition-Competent Human LINE-1 Induces Apoptosis in Cancer Cells With Intact p53

Retrotransposition of human LINE-1 (L1) element, a major representative non-LTR retrotransposon in the human genome, is known to be a source of insertional mutagenesis. However, nothing is known about effects of L1 retrotransposition on cell growth and differentiation. To investigate the potential f...

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Autors principals: Haoudi, Abdelali, Semmes, O. John, Mason, James M., Cannon, Ronald E.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC555774/
https://ncbi.nlm.nih.gov/pubmed/15467158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/S1110724304403131
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