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Human LINE-1 retrotransposon induces DNA damage and apoptosis in cancer cells

BACKGROUND: Long interspersed nuclear elements (LINEs), Alu and endogenous retroviruses (ERVs) make up some 45% of human DNA. LINE-1 also called L1, is the most common family of non-LTR retrotransposons in the human genome and comprises about 17% of the genome. L1 elements require the integration in...

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Autors principals: Belgnaoui, S Mehdi, Gosden, Roger G, Semmes, O John, Haoudi, Abdelali
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464142/
https://ncbi.nlm.nih.gov/pubmed/16670018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-6-13
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