B-type natriuretic peptide overexpression ameliorates hepatorenal fibrocystic disease in a rat model of polycystic kidney disease

Polycystic kidney disease (PKD) involves progressive hepatorenal cyst expansion and fibrosis, frequently leading to end-stage renal disease. Increased vasopressin and cAMP signaling, dysregulated calcium homeostasis, and hypertension play major roles in PKD progression. The guanylyl cyclase A agonis...

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Publicado en:Kidney Int
Main Authors: Holditch, Sara J., Schreiber, Claire A., Harris, Peter C., LaRusso, Nicholas F., Ramirez-Alvarado, Marina, Cataliotti, Alessandro, Torres, Vicente E., Ikeda, Yasuhiro
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557687/
https://ncbi.nlm.nih.gov/pubmed/28416225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2017.02.017
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