A carregar...

Biochemical characterization of recombinant influenza A polymerase heterotrimer complex: Endonuclease activity and evaluation of inhibitors

Influenza polymerase is a heterotrimer composed of polymerase acidic protein A (PA) and basic proteins 1 (PB1) and 2 (PB2). The endonuclease active site, located in the PA subunit, cleaves host mRNA to prime viral mRNA transcription, and is essential for viral replication. To date, the human influen...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Xing, Weimei, Barauskas, Ona, Kirschberg, Thorsten, Niedziela-Majka, Anita, Clarke, Michael, Birkus, Gabriel, Weissburg, Perry, Liu, Xiaohong, Schultz, Brian E., Sakowicz, Roman, Kwon, HyockJoo, Feng, Joy Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557545/
https://ncbi.nlm.nih.gov/pubmed/28809961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181969
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!