Genomic upregulation of cardiac Cav1.2α and NCX1 by estrogen in women

BACKGROUND: Women have a higher risk of lethal arrhythmias than men in long QT syndrome type 2 (LQTS2), but the mechanisms remain uncertain due to the limited availability of healthy control human tissue. We have previously reported that in female rabbits, estrogen increases arrhythmia risk in drug-...

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Detalles Bibliográficos
Publicado en:Biol Sex Differ
Autores principales: Papp, Rita, Bett, Glenna C. L., Lis, Agnieszka, Rasmusson, Randall L., Baczkó, István, Varró, András, Salama, Guy
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557418/
https://ncbi.nlm.nih.gov/pubmed/28807015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13293-017-0148-4
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