A Metabolomics Study of the Effects of Inflammation, Hypoxia, and High Glucose on Isolated Human Pancreatic Islets

The transplantation of human pancreatic islets is a therapeutic possibility for a subset of type 1 diabetic patients who experience severe hypoglycemia. Pre- and post-transplantation loss in islet viability and function, however, is a major efficacy-limiting impediment. To investigate the effects of...

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Udgivet i:J Proteome Res
Main Authors: Garcia-Contreras, Marta, Tamayo-Garcia, Alejandro, Pappan, Kirk L., Michelotti, Gregory A., Stabler, Cherie L., Ricordi, Camillo, Buchwald, Peter
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557342/
https://ncbi.nlm.nih.gov/pubmed/28452488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.7b00160
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