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Preventing hypoxia-induced cell death in beta cells and islets via hydrolytically activated, oxygen-generating biomaterials

A major hindrance in engineering tissues containing highly metabolically active cells is the insufficient oxygenation of these implants, which results in dying or dysfunctional cells in portions of the graft. The development of methods to increase oxygen availability within tissue-engineered implant...

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Detalhes bibliográficos
Main Authors: Pedraza, Eileen, Coronel, Maria M., Fraker, Christopher A., Ricordi, Camillo, Stabler, Cherie L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306668/
https://ncbi.nlm.nih.gov/pubmed/22371586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113560109
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