Specific ion channels contribute to key elements of pathology during secondary degeneration following neurotrauma

BACKGROUND: Following partial injury to the central nervous system, cells beyond the initial injury site undergo secondary degeneration, exacerbating loss of neurons, compact myelin and function. Changes in Ca(2+) flux are associated with metabolic and structural changes, but it is not yet clear how...

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Veröffentlicht in:BMC Neurosci
Hauptverfasser: O’Hare Doig, Ryan L., Chiha, Wissam, Giacci, Marcus K., Yates, Nathanael J., Bartlett, Carole A., Smith, Nicole M., Hodgetts, Stuart I., Harvey, Alan R., Fitzgerald, Melinda
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557315/
https://ncbi.nlm.nih.gov/pubmed/28806920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-017-0380-1
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