Delayed treatment of secondary degeneration following acute optic nerve transection using a combination of ion channel inhibitors

Studies have shown that a combined application of several ion channel inhibitors immediately after central nervous system injury can inhibit secondary degeneration. However, for clinical use, it is necessary to determine how long after injury the combined treatment of several ion channel inhibitors...

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Detalhes bibliográficos
Main Authors: Nathanael J Yates, Marcus K Giacci, Ryan L O'Hare Doig, Wissam Chiha, Bethany E Ashworth, Jade Kenna, Carole A Bartlett, Melinda Fitzgerald
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Medknow Publications 2017-01-01
Colecção:Neural Regeneration Research
Assuntos:
nerve regeneration; optic nerve injury; neurotrauma; secondary degeneration; seromas; calcium channel inhibitor; node of Ranvier; Tau phosphorylation; lipid peroxidation; oxidative stress; neural regeneration
Acesso em linha:http://www.nrronline.org/article.asp?issn=1673-5374;year=2017;volume=12;issue=2;spage=307;epage=316;aulast=Yates
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