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Changes in podocyte TRPC channels evoked by plasma and sera from patients with recurrent FSGS and by putative glomerular permeability factors

Primary forms of focal and segmental glomeruloslerosis (FSGS) are driven by circulating factors that cause dysfunction or loss podocytes. Rare genetic forms of FSGS can be caused by mutations in TRPC6, which encodes a Ca(2+)-permeable cationic channel expressed in mesangial cells and podocytes; and...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Kim, Eun Young, Roshanravan, Hila, Dryer, Stuart E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557291/
https://ncbi.nlm.nih.gov/pubmed/28629718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2017.06.010
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