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Insulin increases surface expression of TRPC6 channels in podocytes: role of NADPH oxidases and reactive oxygen species

Insulin receptors in podocytes are essential for normal kidney function. Here, we show that insulin evokes a rapid increase in the surface expression of canonical transient receptor potential-6 channel (TRPC6) channels in cultured podocytes, but caused a decrease in surface expression of TRPC5. Thes...

詳細記述

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書誌詳細
主要な著者: Kim, Eun Young, Anderson, Marc, Dryer, Stuart E.
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287354/
https://ncbi.nlm.nih.gov/pubmed/22031853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00423.2011
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