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Engineering Therapeutic T Cells: From Synthetic Biology to Clinical Trials

Engineered T cells are currently in clinical trials to treat patients with cancer, solid organ transplants, and autoimmune diseases. However, the field is still in its infancy. The design, and manufacturing, of T cell therapies is not standardized and is performed mostly in academic settings by comp...

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Detalhes bibliográficos
Publicado no:Annu Rev Pathol
Main Authors: Esensten, Jonathan H., Bluestone, Jeffrey A., Lim, Wendell A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557092/
https://ncbi.nlm.nih.gov/pubmed/27959633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pathol-052016-100304
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