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Anoctamins/TMEM16 Proteins: Chloride channels flirting with lipids and extracellular vesicles

Anoctamin/TMEM16 proteins exhibit diverse functions in cells throughout the body and are implicated in several human diseases. Although the founding members ANO1 (TMEM16A) and ANO2 (TMEM16B) are Ca(2+)-activated Cl(−) channels, most ANO paralogs are Ca(2+)-dependent phospholipid scramblases that ser...

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Bibliografiske detaljer
Udgivet i:Annu Rev Physiol
Main Authors: Whitlock, Jarred M., Hartzell, H. Criss
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5556385/
https://ncbi.nlm.nih.gov/pubmed/27860832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-physiol-022516-034031
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