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PHF20 positively regulates osteoblast differentiation via increasing the expression and activation of Runx2 with enrichment of H3K4me3

Plant homeodomain finger protein 20 (PHF20), a methyl lysine effector protein, is a component MOF-NSL lysine acetyltranferase complex. Global deletion of PHF20 has shown spinal bone defects and reduced skeletal formation. However, the molecular basis of PHF20 involved in skeletal development has not...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yang, Jin-Woo, Jeong, Byung-Chul, Park, Jongsun, Koh, Jeong-Tae
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5556080/
https://ncbi.nlm.nih.gov/pubmed/28808306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08868-0
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