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Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners
CAS is a docking protein downstream of the proto-oncogene Src with a role in invasion and metastasis of cancer cells. The CAS SH3 domain is indispensable for CAS-mediated signaling, but structural aspects of CAS SH3 ligand binding and regulation are not well understood. Here, we identified the conse...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5556061/ https://ncbi.nlm.nih.gov/pubmed/28808245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08303-4 |
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