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Gene editing in clinical isolates of Candida parapsilosis using CRISPR/Cas9

Candida parapsilosis is one of the most common causes of candidiasis, particularly in the very young and the very old. Studies of gene function are limited by the lack of a sexual cycle, the diploid genome, and a paucity of molecular tools. We describe here the development of a plasmid-based CRISPR-...

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Publicat a:Sci Rep
Autors principals: Lombardi, Lisa, Turner, Siobhán A., Zhao, Fang, Butler, Geraldine
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5556056/
https://ncbi.nlm.nih.gov/pubmed/28808289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08500-1
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