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p73 and FoxJ1: Programming Multiciliated Epithelia

The mysteriously diverse phenotypes in mice lacking the p53 homolog p73 are recently unified by new analysis showing p73 is required for formation of multiciliated epithelia. p73 directly activates FoxJ1, the central transcriptional driver for multiciliation, and induces a host of genes critical for...

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Bibliographic Details
Published in:Trends Cell Biol
Main Authors: Jackson, Peter K., Attardi, Laura D.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555749/
https://ncbi.nlm.nih.gov/pubmed/26988441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2016.03.001
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