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Evolutionarily Ancient Association of the FoxJ1 Transcription Factor with the Motile Ciliogenic Program

It is generally believed that the last eukaryotic common ancestor (LECA) was a unicellular organism with motile cilia. In the vertebrates, the winged-helix transcription factor FoxJ1 functions as the master regulator of motile cilia biogenesis. Despite the antiquity of cilia, their highly conserved...

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Detalhes bibliográficos
Main Authors: Vij, Shubha, Rink, Jochen C., Ho, Hao Kee, Babu, Deepak, Eitel, Michael, Narasimhan, Vijayashankaranarayanan, Tiku, Varnesh, Westbrook, Jody, Schierwater, Bernd, Roy, Sudipto
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493443/
https://ncbi.nlm.nih.gov/pubmed/23144623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003019
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