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Functional analysis of Na(+)/H(+) exchanger 9 variants identified in patients with autism and epilepsy

Na(+)/H(+) exchanger isoform 9, NHE9, finely tunes the pH within the endosomal lumen to regulate cargo trafficking and turnover. In patients with autism, genetic approaches have revealed deletions, truncations and missense mutations in the gene encoding NHE9 (SLC9A9). To help establish causality, fu...

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Publicado en:Matters (Zur)
Autores principales: Prasad, Hari, Osei-Owusu, James, Rao, Rajini
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555647/
https://ncbi.nlm.nih.gov/pubmed/28815171
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