Evaluation of the Potential for Drug Interactions With Patiromer in Healthy Volunteers

INTRODUCTION: Patiromer is a potassium-binding polymer that is not systemically absorbed; however, it may bind coadministered oral drugs in the gastrointestinal tract, potentially reducing their absorption. METHODS: Twelve randomized, open-label, 3-period, 3-sequence crossover studies were conducted...

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Udgivet i:J Cardiovasc Pharmacol Ther
Main Authors: Lesko, Lawrence J., Offman, Elliot, Brew, Christine Taylor, Garza, Dahlia, Benton, Wade, Mayo, Martha R., Romero, Alain, Du Mond, Charles, Weir, Matthew R.
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2017
Fag:
Clinical Studies
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555446/
https://ncbi.nlm.nih.gov/pubmed/28585859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1074248417691135
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