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Bayesian designs to account for patient heterogeneity in phase II clinical trials
PURPOSE OF REVIEW: Between-patient heterogeneity is very common in clinical trials. This complicates treatment evaluation, due to known prognostic subgroup effects or potential treatment-subgroup interactions. We review two Bayesian phase II clinical trial designs that account explicitly for patient...
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| Udgivet i: | Curr Opin Oncol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5555403/ https://ncbi.nlm.nih.gov/pubmed/18525336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCO.0b013e328302163c |
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